| Game | Region | Rating | Download |
|---|
| SD Hiryuu no Ken EX (SGB Enhanced) (GB Compatible) |  |  | |
| SWiV |  | | |
| Saban's Power Rangers - Lightspeed Rescue |  | | |
| Saban's Power Rangers - Time Force | | | |
| Sabrina - The Animated Series - Spooked! | | | |
| Sabrina - The Animated Series - Zapped! | | | |
| Sabrina - The Animated Series - Zapped! | | | |
| Sakata Gorou Kudan no Renju Kyoushitsu (SGB Enhanced) (GB Compatible) | | | |
| Sakura Taisen GB - Geki Hana Gumi Nyuutai! | | | |
| Sakura Taisen GB 2 - Thunderbolt Sakusen | | | |
| Samurai Kid | | | |
| San Francisco Rush - Extreme Racing (Proto) | | | |
| San Francisco Rush 2049 | | | |
| San Guo Wu Shang 5 (Unl) |  | | |
| Sangokushi - Game Boy Ban 2 (SGB Enhanced) (GB Compatible) | | | |
| Sanguozhi - Aoshi Tianxia (Unl) | | | |
| Sanguozhi Wudai (Unl) | | | |
| Sanrio Timenet - Kako Hen (Rev 1) (SGB Enhanced) (GB Compatible) | | | |
| Sanrio Timenet - Kako Hen (SGB Enhanced) (GB Compatible) | | | |
| Sanrio Timenet - Mirai Hen (Rev 1) (SGB Enhanced) (GB Compatible) | | | |
| Sanrio Timenet - Mirai Hen (SGB Enhanced) (GB Compatible) | | | |
| Santa Claus Junior | | | |
| Saru Puncher (SGB Enhanced) (GB Compatible) | | | |
| Scooby-Doo! - Classic Creep Capers | | | |
| Scrabble | | | |
| Sea-Doo HydroCross (Proto) | | | |
| Sei Hai Densetsu (SGB Enhanced) (GB Compatible) | | | |
| Seme COM Dungeon - Drururuaga (GB Compatible) | | | |
| Senkai Ibunroku Juntei Taisen - TV Animation Senkaiden Houshin Engi Yori (SGB Enhanced) (GB Compatible) | | | |
| Sesame Street - Elmo's 123s (GB Compatible) | | | |
| Sesame Street - Elmo's 123s (GB Compatible) | | | |
| Sesame Street - Elmo's ABCs (GB Compatible) | | | |
| Sesame Street - Elmo's ABCs (GB Compatible) | | | |
| Sesame Street - The Adventures of Elmo in Grouchland (GB Compatible) | | | |
| Sesame Street - The Adventures of Elmo in Grouchland (GB Compatible) | | | |
| Sesame Street Sports | | | |
| Sesame Street Sports | | | |
| Sewing Machine Operation Software (Proto) (GB Compatible) | | | |
| Sewing Machine Operation Software (GB Compatible) | | | |
| Sewing Machine Operation Software (Proto) (GB Compatible) | | | |
| Sewing Machine Operation Software (GB Compatible) | | | |
| Sgt. Rock - On the Frontline | | | |
| Shadowgate Classic (Rev 1) (GB Compatible) | | | |
| Shadowgate Classic (GB Compatible) | | | |
| Shadowgate Return (GB Compatible) | | | |
| Shaman King Card Game - Chou Senjiryakketsu - Funbari Hen | | | |
| Shaman King Card Game - Chou Senjiryakketsu - Meramera Hen | | | |
| Shamus (GB Compatible) | | | |
| Shanghai Pocket (Rev 1) (SGB Enhanced) (GB Compatible) | | | |
| Shanghai Pocket (SGB Enhanced) (GB Compatible) | | | |
| Shanghai Pocket (Rev 1) (Proto) (SGB Enhanced) (GB Compatible) | | | |
| Shanghai Pocket (SGB Enhanced) (GB Compatible) | | | |
| Shantae (Beta) | | | |
| Shantae | | | |
| Shao Lin Shi San Gun - Ying Xiong Jiu Zhu (Unl) | | | |
| Shaoling Legend - Hero, the Saver (Unl) | | | |
| Shaun Palmer's Pro Snowboarder |  | | |
| Shelly Club | | | |
| Sheng Shou Wu Yu - Shen Long Chuan Shuo (Unl) | | | |
| Shengui Diguo Zhi Emo Cheng (Unl) | | | |
| Shi Kong Xing Shou (Unl) | | | |
| Shi Mian Maifu - Fengyun Pian (Unl) | | | |
| Shin Megami Tensei Devil Children - Aka no Sho (Rev 1) (SGB Enhanced) (GB Compatible) | | | |
| Shin Megami Tensei Devil Children - Aka no Sho (SGB Enhanced) (GB Compatible) | | | |
| Shin Megami Tensei Devil Children - Kuro no Sho (Rev 1) (SGB Enhanced) (GB Compatible) | | | |
| Shin Megami Tensei Devil Children - Kuro no Sho (SGB Enhanced) (GB Compatible) | | | |
| Shin Megami Tensei Devil Children - Shiro no Sho (Rev 1) (Proto) | | | |
| Shin Megami Tensei Devil Children - Shiro no Sho | | | |
| Shin Megami Tensei Trading Card - Card Summoner | | | |
| Shinseiki Evangelion - Mahjong Hokan Keikaku | | | |
| Shishang Chaoqiang RPG + Gedou + Yizhi Ban Zuhe Ka 18 in 1 (Unl) | | | |
| Shougi 2 (GB Compatible) | | | |
| Shougi 3 (GB Compatible) | | | |
| Shrek - Fairy Tale Freakdown | | | |
| Shu Ma Bao Long - Ge Dou Ban 2003 (Unl) | | | |
| Shu Ma Bao Long - Shui Jing Ban II (Unl) | | | |
| Shu Ma Bao Long 9 - Bao Long Pian 2002 (Unl) | | | |
| Shu Ma Bao Long Zhuan Ji 10 in 1 (Unl) | | | |
| Shuihu Shenshou (Unl) (Alt) | | | |
| Shuihu Shenshou (Unl) | | | |
| Shuihu Zhuan - Jingdian Ban (Unl) | | | |
| Shuihu Zhuan Zhi Qunmo Fengyun Lu (Unl) |  | | |
| Shuma Baobei - Chao Mengmeng Fanji Zhan | | | |
| Shuma Baobei - Hai Zhi Shen (Unl) | | | |
| Shuma Baobei - Huojian Bingtuan (Unl) | | | |
| Shuma Baobei DX6 (Unl) | | | |
| Shuma Baolong - Diannao Pian (Unl) | | | |
| Shuma Baolong - Koudai Ban (Unl) (Alt) | | | |
| Shuma Baolong - Koudai Ban (Unl) | | | |
| Shuma Baolong - Shuijing Ban (Li Cheng) (Unl) | | | |
| Shuma Baolong - Shuijing Ban (Vast Fame) (Unl) | | | |
| Shuma Baolong 02 4 (Unl) | | | |
| Shutokou Racing, The (SGB Enhanced) (GB Compatible) | | | |
| Simpsons, The - Night of the Living Treehouse of Horror | | | |
| Skelby (Aftermarket) (Homebrew) |  | | |
| Skycon (Aftermarket) (Homebrew) | | | |
| Smurfs Nightmare, The | | | |
| Smurfs Nightmare, The | | | |
| Snobow Champion | | | |
| Snoopy Tennis (Beta) | | | |
| Snoopy Tennis | | | |
| Snoopy Tennis | | | |
| Snoopy Tennis | | | |
| Snow White and the Seven Dwarfs | | | |
| Snow White and the Seven Dwarfs | | | |
| SnowCross | | | |
| Soccer Manager | | | |
| Solomon | | | |
| Sonic Adventure 7 (Unl) | | | |
| Sonic Adventure 8 (Rumble Version) (Unl) | | | |
| Soreike! Anpanman - 5-tsu no Tou no Ousama | | | |
| Soreike! Anpanman - Fushigi na Nikoniko Album (SGB Enhanced) (GB Compatible) | | | |
| Soukoban Densetsu - Hikari to Yami no Kuni (SGB Enhanced) (GB Compatible) | | | |
| Soul Getter - Houkago Bouken RPG (GB Compatible) | | | |
| South Park (Proto) | | | |
| Space Baby (Unl) | | | |
| Space Invaders (GB Compatible) | | | |
| Space Invaders X (GB Compatible) | | | |
| Space Invasion & Karate Joe (Unl) | | | |
| Space Invasion & Painter (Unl) | | | |
| Space Invasion (Unl) | | | |
| Space Marauder | | | |
| Space-Net - Cosmo Blue | | | |
| Space-Net - Cosmo Neo (Proto) | | | |
| Space-Net - Cosmo Red | | | |
| Spacestation Silicon Valley (GB Compatible) | | | |
| Spawn | | | |
| Speedy Gonzales - Aztec Adventure (Proto) (GB Compatible) | | | |
| Speedy Gonzales - Aztec Adventure (GB Compatible) | | | |
| Spider-Man |  | | |
| Spider-Man | | | |
| Spider-Man | | | |
| Spider-Man 2 - The Sinister Six | | | |
| Spider-Man 3 - Movie Version (Unl) | | | |
| Spirou - The Robot Invasion | | | |
| SpongeBob SquarePants - Legend of the Lost Spatula | | | |
| Spy vs Spy (Rev 1) (Proto) | | | |
| Spy vs Spy | | | |
| Spy vs Spy (Rev 1) | | | |
| Spy vs Spy | | | |
| Spy vs Spy (Rev 1) (Proto) | | | |
| Spy vs Spy | | | |
| Star Heritage (Proto) (Password Version) | | | |
| Star Heritage (Proto) (SRAM Version) | | | |
| Star Ocean - Blue Sphere (SGB Enhanced) (GB Compatible) | | | |
| Star Trek (Proto) | | | |
| Star Wars - Yoda Stories (GB Compatible) | | | |
| Star Wars Episode I - Obi-Wan's Adventures | | | |
| Star Wars Episode I - Obi-Wan's Adventures | | | |
| Star Wars Episode I - Racer (Rumble Version) | | | |
| Startled 911 (Unl) | | | |
| Stellar Wars (Aftermarket) (Homebrew) | | | |
| Stranded Kids (SGB Enhanced) (GB Compatible) | | | |
| Street Fighter Alpha - Warriors' Dreams (Rev 1) (Proto) | | | |
| Street Fighter Alpha - Warriors' Dreams | | | |
| Street Fighter Alpha - Warriors' Dreams | | | |
| Street Fighter Alpha - Warriors' Dreams | | | |
| Street Hero (1B-004, EB-004, Sachen) (Unl) | | | |
| Stuart Little - The Journey Home | | | |
| Stuart Little - The Journey Home | | | |
| Super 16 in 1 (Sachen) (Unl) | | | |
| Super 6 in 1 (6B-001, Sachen) (Unl) | | | |
| Super Black Bass - Real Fight (Rumble Version) | | | |
| Super Black Bass Pocket 3 (SGB Enhanced) (GB Compatible) | | | |
| Super Bombliss DX (SGB Enhanced) (GB Compatible) | | | |
| Super Breakout! (GB Compatible) | | | |
| Super Breakout! (GB Compatible) | | | |
| Super Chinese Fighter EX | | | |
| Super Doll Licca-chan - Kisekae Daisakusen | | | |
| Super Donkey Kong 5 (Rumble Version) (Unl) (Alt) | | | |
| Super Donkey Kong 5 (Rumble Version) (Unl) | | | |
| Super Fighters 99 (SGB Enhanced) (Unl) | | | |
| Super Gals! Kotobuki Ran | | | |
| Super Gals! Kotobuki Ran 2 - Miracle Getting | | | |
| Super Jacked Up Tomato Face Johnson (Aftermarket) (Homebrew) | | | |
| Super Mario Bros. Deluxe (Rev 2) | | | |
| Super Mario Bros. Deluxe (Rev 1) | | | |
| Super Mario Bros. Deluxe | | | |
| Super Mario Bros. Deluxe (Rev 1) | | | |
| Super Mario Bros. Deluxe | | | |
| Super Mario Special 3 (Unl) | | | |
| Super Marrio Sunshine (Unl) | | | |
| Super Me-Mail GB - Me-Mail Bear no Happy Mail Town | | | |
| Super Nenas, Las - El Malvado Mojo Jojo |  | | |
| Super Nenas, Las - Lucha Con Ese | | | |
| Super Nenas, Las - Panico en Townsville | | | |
| Super Real Fishing (Rumble Version) | | | |
| Super Robot Pinball | | | |
| Super Robot Taisen - Link Battler (SGB Enhanced) (GB Compatible) | | | |
| Supercross Freestyle | | | |
| Superman - Battle for Metropolis (Proto) (2001-01-12) (GB Compatible) | | | |
| Supershot Golf Robot (Proto) | | | |
| Supreme Snowboarding | | | |
| Survival Kids (SGB Enhanced) (GB Compatible) | | | |
| Survival Kids - Kotou no Boukensha (SGB Enhanced) (GB Compatible) | | | |
| Survival Kids 2 - Dasshutsu!! Futago-Jima! (Rev 1) (SGB Enhanced, GB Compatible) | | | |
| Survival Kids 2 - Dasshutsu!! Futago-Jima! (SGB Enhanced) (GB Compatible) | | | |
| Suske en Wiske - De Tijdtemmers ~ Bob et Bobette - Les Dompteurs du Temps (Beta 1) | | | |
| Suske en Wiske - De Tijdtemmers ~ Bob et Bobette - Les Dompteurs du Temps (Beta 2) | | | |
| Sutte Hakkun GB (Proto) | | | |
| Suzuki Alstare Extreme Racing | | | |
| Suzuki Alstare Extreme Racing (Proto) | | | |
| Sweet Ange (SGB Enhanced) (GB Compatible) | | | |
| Swing (Proto) | | | |
| Swing |  | | |
| Sylvanian Families - Otogi no Kuni no Pendant (SGB Enhanced) (GB Compatible) | | | |
| Sylvanian Families 2 - Irozuku Mori no Fantasy (Rev 1) | | | |
| Sylvanian Families 2 - Irozuku Mori no Fantasy | | | |
| Sylvanian Families 3 - Hoshi Furu Yoru no Sunadokei | | | |
| Sylvanian Melodies - Mori no Nakama to Odori Masho! (SGB Enhanced) (GB Compatible) | | | |
| Sylvester & Tweety - Breakfast on the Run (GB Compatible) | | | |
